Common Manifestations
Presentation varies with disease stage, duration, comorbidity burden, and the organ system involved. Some features are intermittent and nonspecific, whereas others point more strongly toward inflammation, structural injury, endocrine disturbance, neurovascular change, or progressive loss of function.
- Right upper quadrant or epigastric pain
- Jaundice or dark urine
- Nausea or intolerance of fatty foods
- Steatorrhea or chronic diarrhea
- Weight loss or nutrient deficiency
- Ascites, edema, or easy bruising