Common Manifestations
Presentation varies with disease stage, duration, comorbidity burden, and the organ system involved. Some features are intermittent and nonspecific, whereas others point more strongly toward inflammation, structural injury, endocrine disturbance, neurovascular change, or progressive loss of function.
- Heartburn or regurgitation
- Abdominal pain or bloating
- Diarrhea or constipation
- Nausea or vomiting
- Rectal bleeding or anemia
- Weight loss or fatigue