Common Manifestations
Presentation varies with disease stage, duration, comorbidity burden, and the organ system involved. Some features are intermittent and nonspecific, whereas others point more strongly toward inflammation, structural injury, endocrine disturbance, neurovascular change, or progressive loss of function.
- Pruritus or burning
- Erythema or scaling
- Papules, plaques, or pustules
- Dry skin or fissuring
- Pigment change or flushing
- Localized or widespread rash